Xanatos employed Sevarius to create the Mutates as a means of giving him a substitute clan of gargoyles, after it became clear that Goliath and his clan would not serve him. Sevarius used three combined originals for the Mutates: jungle cats for their strength and speed, bats to provide wings, and electric eels to provide the Mutates with enough energy to fly through their electroreceptors, and also the ability to fire out bolts of electricity as weapons.
Xanatos’s scheme did not proceed as well as he had hoped, however. While the Mutates did serve him for a while, believing that he was the only one who could turn them back into humans, they finally learned that he had arranged for their mutation all along in order to make them into his flunkeys, and broke away from him. Instead, they went to live in the Labyrinth, where under Talon’s leadership, they took many of the homeless people in New York under their protection.
Further information on Talon, Maggie, Claw, and Fang can be found in their individual entries.
The Mutates’ condition will not be cured; they will remain Mutates for the rest of their lives.